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For a 10 mg lyophilized vial: At 2.5 mg/week: 4 weeks of doses (perfectly matches the 28-day stability window) At 5 mg/week: 2 weeks of doses (well within stability limits) For a 30 mg lyophilized vial: At 2.5 mg/week: 12 weeks of doses (far exceeds 28-day window, significant waste) At 5 mg/week: 6 weeks (exceeds window by 2 weeks) At 7.5 mg/week: 4 weeks (perfect alignment) At 10 mg/week: 3 weeks (fully within stability limits) The reconstitution volume you choose affects how easy it is to measure each dose but does not change these timelines

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[DOI] [PubMed] [Google Scholar] Scopa C., Marrocco F., Latina V., Ruggeri F., Corvaglia V., La Regina F., Ammassari-Teule M., Middei S., Amadoro G., Meli G